Bio-ClusterGrid
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Overview

The Bio-ClusterGrid is the first of many deployment architectures that realizes the benefit of the BioBox initiative.

Objectives
  • To enable biologists harness the power of a clustergrid through a web interface
  • To simplify and speed up the installation of a cluster running bioinformatics applications
  • To provide a portal interface to command line applications
  • To evenly distribute jobs in a cluster

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How Does it Work?

More than 20 of the most popular bioinformatics applications are made available on the Bio-ClusterGrid through the portal, which greatly enhances application usability. Biologists access the portal either through a browser in Sunray Thin Clients in the access tier or through any browser enabled device. The Grid Engine software provides the resource management mechanism to schedule all the bioinformatics applications to run on the cluster of execution servers.


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Components

The core components of the Bio-ClusterGrid are:
  • Operating System (Linux/Solaris)
  • Job Scheduler (Sun Grid Engine)
  • Grid Engine Portal running on Sun Java System Portal Server
  • More than 20 pre-compiled and tested bioinformatics applications that is provided by APBioNet

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Version 1.5 (Current Version)

Version 1.5 Components
  • Java Enterprise System Portal Server 2005Q4
  • Sun Grid Engine 6.1
  • Bioinformatics application binaries
  • Bioinformatics applications intergration scripts

Version 1.5 System/Platform Requirements

Bio-ClusterGrid Master Nodes
  • Solaris 10 on 32-bit x86
  • Solaris 10 on x64
  • RHEL 3.0 AS/WS/ES update 4 (32-bit only)
Bio-ClusterGrid Compute Nodes
  • Solaris 10 on 32-bit x86
  • Solaris 10 on x64
  • RHEL 4.0 WS (x86_64) and similar
Version 1.5 Applications

The list of applications are as follows. To view the complete list of applications availability of different platform and the compatibility matrix, download the BCG 1.5 Applications List.

Application Suites EMBOSS
Development Tools Biojava Bioperl Biopython
Gel Image Processing Image
Gene Finder GlimmerM*
Gene Mapping Mapmaker/QTL
Homology & Similarity Search BLAST* FASTA* Wise2*
Molecular Dynamics GROMACS
Molecular Modeling NAMD* NAB*
Phylogeny FastDNAml* PAML* PHYLIP*
Protein Analysis LOOPP* TribeMCL
Sequence Analysis ClustalW* HMMER* T-Coffee*
Sequence Conversion Readseq*
Structural Analysis DOWSER*
Viewer ACT Artemis Cn3D
Visualisation NMRView Rasmol* VMD

*Portal enabled applications

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Version 1.4

Version 1.4 Update 2 Components
  • Java Enterprise System Portal Server 2005Q4
  • N1 Grid Engine 6 Update 4
  • Bioinformatics application binaries
  • Bioinformatics applications intergration scripts

Version 1.4 Update 2 System/Platform Requirements

Bio-ClusterGrid Master Nodes
  • Solaris 9/10 on SPARC
  • Solaris 10 on 32-bit x86
  • Solaris 10 on x64
  • RHEL 3.0 AS/WS/ES update 4 (32-bit only)
  • ROCKS 3.3.0 i386
Bio-ClusterGrid Compute Nodes
  • Solaris 9/10 on SPARC
  • Solaris 10 on 32-bit x86
  • Solaris 10 on x64
  • RHEL 3.0 WS (x86_64) and similar
  • ROCKS 3.3.0 x86_64

Version 1.4 Update 2 Applications

The list of applications are as follows. To view the complete list of applications availability of different platform and the compatibility matrix, download the BCG 1.4 Applications List.

Application Suites EMBOSS
Development Tools Biojava* Bioperl Biopython
Gel Image Processing Image
Gene Finder GlimmerM*
Gene Mapping Mapmaker/QTL
Homology & Similarity Search BLAST* FASTA* Wise2*
Molecular Dynamics GROMACS
Molecular Modeling NAMD*
Phylogeny FastDNAml* PAML* PHYLIP*
Protein Analysis LOOPP* TribeMCL
Sequence Analysis ClustalW* HMMER* T-Coffee*
Sequence Conversion Readseq*
Structural Analysis DOWSER*
Viewer ACT Artemis* Cn3D
Visualisation NMRView Rasmol* VMD

*Portal enabled applications

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Bio-ClusterGrid for ROCKS 3.3.0



The ROCKS 3.3.0 version of Bio-ClusterGrid has been developed by South China University of Technology - Network Center (SCUT-NC) under the ChinaGrid project. The project team consisted of:

Project Director
  • Dr. Dong Shoubin
Teachers
  • Dr. Yuan Hua
  • Ning Guoning
Students
  • Yue Qiang
  • Liu Pengfei
  • Chen Xiaofeng
ROCKS 3.3.0 Components
  • Java Enterprise System Portal Server 2005Q4
  • Sun Grid Engie 5.3
  • Bioinformatics application binaries roll
  • Bioinformatics applications intergration scripts

ROCKS 3.3.0 System/Platform Requirements

Bio-ClusterGrid Master Nodes
  • ROCKS 3.3.0 i386
Bio-ClusterGrid Compute Nodes
  • ROCKS 3.3.0 x86_64

Please refer to the 'Guides & Documentations' link above for the installation guide. If you would like to receive a copy, please email engage-apstc@sun.com

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Future Plans
  • Inclusion of MPI applications

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